Startup Support in the Age of Agentic AI
Bloomberg Associates · Economic Development · September 2026

Startup Support in the Age of Agentic AI

A practical guide for cities. What a city can do so that its residents and businesses benefit from the way AI is changing how companies are started, built, funded and located.

Three numbers frame the problem
524kUS business applications a month in 2026, up 79% on 2019. Most of them are one-person businesses, which is not the population the standard startup playbook was built for.Census
43%of all venture capital worldwide in the first half of 2026 went to two companies, OpenAI and Anthropic. No city can compete with that, so what a city does control is customers and rules.Crunchbase
6 mofor 10% of businesses started in 2025 to pay for an AI service; the 2019 cohort took 77 months. New founders need no help adopting AI. The firms already trading do.JPMorganChase Institute

Two kinds of businesses

Venture-scale technology startups

Founders who raise outside capital and aim for fast growth. Few and concentrated: 3,500 AI venture deals worldwide in the first half of 2026 (PitchBook), 52% of US pre-seed capital in California (Carta).

AI-enabled small firms and solo founders

Businesses one or two people can run. Many and dispersed: about 524,000 US business applications a month in 2026, fewer than three in ten expected to hire (Census).

The two groups are moving in opposite directions. Venture capital is concentrating while the number of small new businesses is rising, which means a city's options differ for each.

The before and after line is November 2022The public release of ChatGPT. Every study that measures a change in startup formation uses that date. Agentic tools, which carry out multi-step work rather than answer a prompt, arrived on top of it from 2024.
AI-native startupA company with AI at the core of its product, market or business model, which would not exist without AI (Startup Genome).
Big city, small cityBig: already has a venture ecosystem, in PitchBook's 2026 rankings or Brookings' top two AI-readiness tiers, or is a national capital of venture activity such as London, Paris, Berlin, São Paulo or Mexico City. Small: everywhere else.
Part 2 · Playbook

Ten actions

Each action tackles one of the seven problems.

Every initiative below was delivered and tested by other institutions.

Where to start: big city, small city

Big city: has a venture ecosystem already, in PitchBook's 2026 rankings or Brookings' top two AI-readiness tiers (San Francisco and San José, then 28 star hubs including New York, Boston, Seattle, Austin, Chicago and Washington), or a national capital of venture activity such as London, Paris, Berlin, São Paulo or Mexico City. Small city: everywhere else.

The problems are the same everywhere. What changes is which action does the work.

Part 3 · Readings

Everything behind the numbers

Sources marked cited are quoted directly in Parts 1 and 2, and additional readings.